Bad Syndrome

Void mechanisms
Voiding begins when a voluntary signal is sent from the brain to begin urination, and continues until the bladder is empty.

Bladder afferent signals ascend the spinal cord to the periaqueductal gray, where they project both to the pontine micturition center and to the cerebrum. At a certain level of afferent activity, the conscious urge to void becomes difficult to ignore. Once the voluntary signal to begin voiding has been issued, neurons in pontine micturition center fire maximally, causing excitation of sacral preganglionic neurons. The firing of these neurons causes the wall of the bladder to contract; as a result, a sudden, sharp rise in intravesical pressure occurs. The pontine micturition center also causes inhibition of Onuf's nucleus, resulting in relaxation of the external urinary sphincter. When the external urinary sphincter is relaxed urine is released from the urinary bladder when the pressure there is great enough to force urine to flow out of the urethra. The micturition reflex normally produces a series of contractions of the urinary bladder.

The flow of urine through the urethra has an overall excitatory role in micturition, which helps sustain voiding until the bladder is empty.

Disenanglement ("Brain Combing")
Disentanglement puzzles (also called entanglement puzzles, tanglement puzzles, tavern puzzles or topological puzzles) are a type or group of mechanical puzzle that involves disentangling one piece or set of pieces from another piece or set of pieces. Several subtypes are included under this category, the names of which are sometimes used synonymously for the group: wire puzzles; nail puzzles; ring-and-string puzzles; et al. Although the initial object is disentanglement, the reverse problem of reassembling the puzzle can be as hard as—or even harder than—disentanglement. There are several different kinds of disentanglement puzzles, though a single puzzle may incorporate several of these features.